Journal of ISSN: 2373-4310 JNHFE

Nutritional Health & Food Engineering
Journal of Nutritional Health & Food Engineering (JNHFE) is aimed towards providing internationally reviewed and accepted Open Access research contents which includes facts and research results about nutrition and health. It is believed that proper health can be achieved by proper and nutritional intake of food. Hence, this journal provides comprehensive details for those scholars who are interested in Food Engineering and wellness programs in different settings. The journal also provides a platform for health and recreation programs which will enhance not only the physical but also mental fitness. The Journal is pleased to accept different types of content which may include but is not restricted to original submissions. The journal cordially invites Research Papers, Review Articles, Short Communications, Case Reports, Mini- Review, Opinions, Letter to Editors etc., for the latest ongoing and future research.
Email: nutrifood@medcraveonline.org, nutrifood@medcraveonline.us

Latest Articles

Editorial
Journal of Nutritional Health & Food Engineering - January 16, 2017
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Mini Review

Increased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose Diet

Increased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietAgeing is a universal, multifactorial phenomenon, determined by genetic and environmental factors such as diet, stress etc. Diet associated disorders are widely prevalent in India and have been attracting much attention and research in recent times, mostly due to increased awareness among population of the importance of nutrition and balanced diet. Adaptation of western lifestyle (eg. consupmtion of calorie rich, high fat foods, lack of physical activity etc) has increased the prevalence of metabolic disorders like obesity, hypertension, Type 2 Diabetes, cardiovascular diseases etc. It is known that obesity and diabetes per se accelerate ageing, but it is not clear whether or not superimposing diabetes on obesity accelerates ageing. We tested the hypothesis that superimposing Type 2 Diabetes/aggravated insulin resistance on obesity accelerates ageing, by chronic feeding of high sucrose diet (HSD) to WNIN/Gr-Ob, the obese mutant rats of NIN, which aggravated insulin resistance significantly in these obese rats. The survival analysis by Kaplan Meier plot showed decreased longevity in HSD fed rats compared to controls fed starch based diet and in line, cumulative hazard was also higher in HSD fed rats than controls. While the finding that the total DNA damage, an important ageing marker, was significantly higher in HSD fed than control rats appears to confirm the reduced longevity / accelerated ageing in them, the significantly lower telomere length in the liver and brain of HSD fed rats than their age and sex matched control rats fed starch based diet, after 6 months on their respective diets appears to unequivocally demonstrate the accelerated ageing / decreased longevity in HSD fed WNIN/Gr-Ob rats. Our results support the hypothesis that aggravating insulin resistance in obese rats through high sucrose feeding decreases longevity / accelerate aging.Increased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose Diet Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose DietIncreased Macromolecular Damage Underlies the Decreased Longevity of Wnin/Gr-Ob Rats Fed High Sucrose Diet
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Abbreviations: HSD: High Sucrose Diet, SBD: Starch Based Diet, WNIN/Gr-Ob: Wistar National Institute of Nutrition Obese rats, HOMA IR: Homeostatic model assessment Insulin Resistance, AUC: Area Under Curve, OGTT: Oral Glucose Tolerance Test, ROS: Reactive Oxygen Species.
Introduction
Ageing is a universal phenomenon, defined as the process of gradual and
Journal of Nutritional Health & Food Engineering - January 04, 2017
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Research Article
Journal of Nutritional Health & Food Engineering - December 28, 2016
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Research Article
Journal of Nutritional Health & Food Engineering - December 20, 2016
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Research Article
Journal of Nutritional Health & Food Engineering - December 19, 2016
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Review Article
Journal of Nutritional Health & Food Engineering - December 15, 2016
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Research Article
Journal of Nutritional Health & Food Engineering - December 06, 2016
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Research Article
Journal of Nutritional Health & Food Engineering - December 02, 2016
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Research Article
Journal of Nutritional Health & Food Engineering - December 01, 2016
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Opinion
Journal of Nutritional Health & Food Engineering - November 28, 2016
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