Bangladesh is a land of tropical forests and boggy jungle. As boasted with floral genetically plantation of herbs made it an excellent source of medicinal plants. The modern analysis of herbal plants designed with highly esteemed source of medicine to treat Diabetes mellitus. On these consequences the researcher illustrated the local application of raw medicinal products of herbs as a remedy of controlling diabetes. Herbal practitioner in Bangladesh both registered and nonregistered traditionally use some of the herbal plants and active chemical constituents which have a role in the management of Diabetes including type 1 and type 2. The research protocols is subjected as local implementation of home yard medicinal plant to control diabetes in a minimal cost reviewing for its anti diabetic activity without side effects.

Keywords: amyline antagonism, cAMP, diabetes mellitus, insulinotropic, phytomedicine, herbal practitioner

Bangladesh created own environmental support for tree plantation due to its monsoon effects. The concern of isolation and identification of phytomedicinal plants based on tropical rain forest area in Bangladesh is subjected on these global effects. For this reason, the research work has been carried out at Chittagong metropolitan and rural based area in Bangladesh. Here the reviewers tried to follow up differentiate implementation of raw herbal products for the treatment of Diabetic patient collected from home yard ground. Inexpensive and easily accessible nature of the traditional medicines made it an integral part of public health services in Bangladesh. Diabetes mellitus is metabolic diseases characterized in group of patterns incorporate with high blood sugar (glucose) levels that result from insufficient insulin secretion.¹ Phyto medicines have been highly esteemed source are widely used today indicating that herbs usually inconsideration growing part of modern Bio tech application.² Home yard herbal plants with active chemical constituents play a vital role in the treatment of Diabetes mellitus type 1 and type 2 maintaining blood sugar level in normal 70 to 100, or less than 140 mg/100ml.^3,4 The Ayurvedic village prescribers were compiled along with their specific treatment and authentic suggestion as use this raw medicine discussed in this review.

The herbal practitioner suggested comfortless and effective ways to practice medicine for diabetic treatment depending on home yard source.⁵ Natural home yard plants, crops, seeds, leaves considered as performing potent candidates with pharmaceutical synthetic oral medicines.⁶ So steps should be taken from root label to optimize a procedure for ant diabetic screening of different plant extracts isolating new bioactive compounds for the discovery of home yard available herbal anti diabetic drugs.⁷ Herbal village practitioner chose Fenugreek (Trigonellafoenum-graecum L., family Leguminasae) seeds due to its active components 4-HI (4-hydroxyisoleucine), this potential active compound is applied on diabetic patient in a successive patterns. Another available source of application is chosen by the ayurvedic doctors Neem (Azadirachtaindica, mahogany family).⁸ The present study evaluated the long term hypoglycemic effect of Black cumin (Nigella sativa) holy basil (Ocimum sanctum), Cherotha (Swertiachirayita), Seeds of Mehogone (Swieteniamacrophylla), Bitter gourd (Momordicacharantia L.) to treat as yard plenty ailments based on activities regarding anti diabetic application. The in vitro application of aqueous extract of aloevera (Aloe barbadensis) leaves examined for its anti diabetic activities against alloxan induced diabetic mice. But aloevera maintains a long term hypoglycemic effect accordance with observational studies of village herbal practitioner,^9,10 proved the basic fundamentals need of diabetic patient.¹¹

Isolation and Identification of home yard anti diabetic plants:

Collection of authentication

The plant used in this study was collected from the stand at the courtyard around the Dean’s Office, Botanical garden, Home yard garden of ayurvedic doctor and Faculty of Biological Sciences, University of Chittagong. The specimens were authenticated by Dr. Shaikh Bokhtear Uddin, a botanist in the Department of Botany, University of Chittagong

Azadirachtaindica Momordicacharantia Aloe barbadensis

Catharanthus roseus Capparisdeciduas Ocimum sanctum

Terminaliachebula, Allium cepa, Allium sativum. Swieteniamacrophylla

Field survey

A total of twenty Herbal practitioners have been interviewed. They have age group between 35-50. In this contrary approaching honored by at least 10 to 25years experience. So following nine practitioners were selected for their logical arguments and also for effective prescriber.

Preparation of anti diabetic suspension

Saturate solution of Neem leaves (over night): 250 ml

Fenugreek: 20gm

Alovera gel: 10gm

Seeds of Mehogone: 5gm

Natural resources considered as potent candidates for drug discovery and are playing a pivotal role in drug development programs. Moreover, many medicinal herbs provide a rich mine for bioactive chemicals that are markedly free from undesirable side effects and of powerful pharmacological actions.^12–14

Twenty Herbal practitioners have been interviewed remedies the herbs as medicine. They have age group between 35-50. In this contrary approaching honored to them by at least 10 to 25years experience. So following nine practitioners (Table 1) were selected for their logical arguments as for effective prescriber. A total of 17 species have been found to be used for the treatment of diabetes in 16 /genera under six Families and subjected to Herb, shrub, tree and climber. From the analysis of herbal formularies, it has been observed that the percentage of use of plant parts contain 37% leaves, 17% entire plant, 16% seed, 14% Fruit, 6% Flower, 4% Bulb, 6% Bark (Figure 1). Than the researcher and associates selected twelve home yard phytomedicinal plants and their remedies upon patient for three months (Table 2). The ayurvedic village doctor practices their home made medicines where as their patient became cure from their outdoor suggestion (Figure 2).

Figure 1 Analysis of remedies obtained from different plant parts for Diabetes Mellitus 1. L - Leaves, 2. EP - Entire plant, 3. S - Seed, 4. F - Fruit, 5. FL - Flower, 6.B - Bulb, 7. BR – Bark.

Figure 2 Preparation of Anti Diabetic Suspension by Ayurbedic village doctor Md. Najmul Hasan.

The research survey continued with daily assessment of history in diabetic and non diabetic patients being with administered specific isolated plant medicine by respective doctor. Medicinal plants that have been shown to improve the diabetic state without apparent enhancement of insulin secretion tested for effective constituents of raw alkaloids properties suggested by Ayurvedic village doctors (Figure 3 & Figure 4). The constituents and active properties regarding hypoglycemic effect and antibiotic sensitivity has been studied and observed by researcher from several blood reports of patients in a collective profile (Table 3). From this group study and research survey, the outcomes resulted about self home remedies for diabetic patient in regular practice at a minimal cost. Garlic, onion and fenugreek (48.57%, 60% and 76.73% curability rate) is very much effective to maintain hypoglycemic level in both diabetic and non diabetic patients. Blackberry, hollybasil and aloevera cultivation is the good source for home yard cultivation due to antibiotic and antidiabetic effects on patients without having any discomfort for its own chemical components. These include eugenol, linalool, estragole, limonene, citral, methylchavicol, and methyl cinnamate. The more distinctly scented varieties boast a predominant volatile compound that out-competes the rest, producing a characteristic aroma.

Figure 3 Ayurbedic village doctor Md. Najmul Hasan showed home yard medicinal plants, and home made medicinal ingredients from leaves, bark, fruits and roots.

Figure 4 Ayurvedic village doctor Mr. Ghandhi Das showed home yard medicinal plants and its fruits with roots.

Momordin, Ophelic acid and Stearic acid produced acidity in stomach accelerating the receptor of hydrogen antagonistic to probiotic production. Indigestion may result if generic Compound is administered in fasting condition of patient. So the raw juice of Neem (58.93%curability rate) leaves, Cherotha and Bitter gourd (56.44% curability rate) should be suggested in 200ml daily considerable in age 35-55. This medicine should not be prescribed to complete insulin dependent patient. So the curability rate comes out as best suggestive for Bitter gourd for type 1 and Cherotha is suggestive for type 2. But as regular practice to control sugar label as preventive medicine, Cherotha (75.11%curability rate) is the best selection for practitioner. Telakucha and Noyontara is less effective than others and it may also cause ulceration to intestine of immune suppressed patient. So the ayurvedic practitioners suggest as observing the history and blood report of diabetic patients. The graphical presentation Figure 5–8 showed the diagrammatic points of view that already been described in noted discussion.

Figure 5 Graphical views of comparative study among the isolated phytomedicinal plants.

Figure 6 Fluctuation points are noted as curability percentages among isolated plants in Type1 diabetes patients.

Figure 7 Fluctuation points are noted as curability percentages among isolated plants in Type 2 diabetes patients.

Figure 8 Curability percentages among isolated plants in Type1 and Type 2 diabetes Patients.

The phytomedicinal condition of different samples and their safety assessment revealed that most of the raw medicinal residues as a treatment were acceptable. The implemented safety of the samples depend not only the environmental conditions but also on the personal medication and doctors suggestion. Detailed study is required concerning more areas, increasing more sampling sites and their numbers for better growth of home yard medicinal plants. Storage duration of home yard phytomedicinal plants plays an important vital role and long storage duration favors more carcinogenic and chemical toxin degrading gradually their remedies potency. Therefore storage of processed raw medicine for long time should always be avoided and prohibited. As most of the plants constituents are able to produce toxins, it is necessary to monitor strictly medicinal products and then certify them for human consumption after performing a dose to patient.

None.

The authors declare that there is no conflicts of interest.

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