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Case Report Volume 3 Issue 1
Electro-chemotherapy in a case of oral squamous cell carcinoma: case report and consideration
Shanmugha kumar,1 Madullika ,1 Manohara Prasad E,2 Sasi Kumar S 2
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1Govt General Hospital, India
2OnMed India Pvt Ltd., India
Correspondence: Sasi Kumar S, OnMed India Pvt Ltd., No 243/8th Block, KKD Nagar, Chennai-118, India, Tel 91-99140424174
Received: January 26, 2015 | Published: July 28, 2015
Citation: Kumar S, Madullika, Manohara PE, et al. Electro-chemotherapy in a case of oral squamous cell carcinoma: case report and consideration. J Cancer Prev Curr Res. 2015;23(1):199. DOI: 10.15406/jcpcr.2015.03.00065
Abstract
Background: Squamous Cell Carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been major opinion for its treatment. ECT is a novel local treatment successfully used in secondary or primary skin or subcutaneous treatment.
Methods: we report a case of man affected by Squamous cell carcinoma male patient, aged 51 diagnosed with squamous cell carcinoma (SCC). Had pain, difficulty in swallowing and talking. Patient was treated with ECT with Eight, 1000V/cm, 100µs pulses were applied using Sennex electroporator. Results Two ECT sittings with 2 weeks interval were given and the tumor volume reduced significantly, enhancing the quality of life. Figure 1 shows the tumor, before and 12 days after treatment.
Conclusion: The Tumor volume reduced almost 90% shows good clinical results.
Background
Squamous Cell Carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been major opinion for its treatment. ECT is a novel local treatment successfully used in secondary or primary skin or subcutaneous treatment.
Methods
We report a case of man affected by Squamous cell carcinoma male patient, aged 51 diagnosed with squamous cell carcinoma (SCC). Had pain, difficulty in swallowing and talking. Patient was treated with ECT with Eight, 1000V/cm, 100µs pulses were applied using Sennex electroporator.
Results
Two ECT sittings with 2 weeks interval were given and the tumor volume reduced significantly, enhancing the quality of life. Figure 1 shows the tumor, before and 12 days after treatment.
Figure 1 Head & Neck Cancer Patient 1 (before treatment (left), 12 days after treatment (right).
Conclusion
The Tumor volume reduced almost 90% shows good clinical results.1–4
Acknowledgments
None.
Conflicts of interest
The authors have no financial conflicts of interest to declare.
Funding
None.
References
- Kulkrni MK. Head and neck cancer burden in India. Int J of Head and Neck Surgery. 2013;4(1):29–35.
- Gehl J, Geertsen PF. Efficient palliation of haemorrhaging malignant melanoma skin metastases by electrochemotherapy. Melanoma Res. 2000;10(6):585–589.
- Campana LG, Mocellin S, Basso M, et al. Bleomycin–based electrochemotherapy:clinical outcome from a single Institution’s experience with 52 patients. Ann Surg Oncol. 2009;16(1):191–199.
©2015 Kumar, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.