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Cancer Prevention & Current Research

Review Article Volume 17 Issue 2

Anticancer properties of soursop (Annona muricata): an updated review

Sohail Ahmad Jan, Kainat Ikhlaq

Department of Bioinformatics and Biosciences, Capital University of Science and Technology, Islamabad, Pakistan

Received: March 15, 2026 | Published: March 30, 2026

Citation: Ikhlaq K, Jan SA. Anticancer properties of soursop (Annona muricata): an updated review. J Cancer Prev Curr Res. 2026;17(2):41‒42. DOI: 10.15406/jcpcr.2026.17.00604

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Abstract

Cancer remains a major cause of mortality worldwide, highlighting the urgent need for the development of novel therapeutic agents with enhanced efficacy and improved safety profiles. Annona muricata (Soursop), which is endemic to tropical regions of the Americas, is well-known for its tasty fruit and traditional medicinal uses. Several portions of the plant, including the leaves, bark, and seeds, contain bioactive compounds. Several studies have reported that the leaves exhibit stronger anticancer activities against different types of cancer. Both wet lab and In-silico studies support the potential of soursop leaves as a beneficial alternative treatment for managing cancer. In the last 2–3 years, several researchers have reported highly significant anticancer effects against various cancer types when used either as a single dose or in combination with other therapeutic drugs. Overall, the current review highlights that A. muricata exhibits a promising anticancer profile. Nevertheless, further research, particularly clinical studies involving human subjects with different types of cancer, is required to confirm its safety and therapeutic efficacy.

Keywords: Annona muricata, anticancer, cancer, clinical studies, safety

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©2026 Ikhlaq, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.