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Review Article Volume 3 Issue 7
Correlations between Inflammation and Development of Cancer, A Small Review
Jayita Goswami
Received: December 07, 2016 | Published: December 28, 2016
Citation: Goswami J (2016) Correlations between Inflammation and Development of Cancer, A Small Review. J Anal Pharm Res 3(7): 00082. DOI: 10.15406/japlr.2016.03.00082
Abstract
Infection and inflammation are the critical parameters towards developing cancer in the human. Current research interest established that inflammation can lead to chromosomal breakage and development of cancer. Reactive oxygen species (ROS) is one of the key element that takes charge of redox potential followed by protein’s conformational change and cancer development. After infection and inflammation, the production of ROS and nitric oxide (NO) activates several cells signaling pathways; which eventually down-regulate some of the essential protein or enzyme’s activities. A big range of bacteria and viruses showed the capabilities to initiate cancer. The passive electromagnetic force is also another key element in abnormal gene shuffling during cell division and cancer development. The loss of redox control is the hallmark of cancer formation. People emerged in cell-based therapies that mean training immune cells to battle with microbes. In this paper, several important proteins and enzymes activities are discussed up to subcellular level.
Keywords: Inflammation, Infection, Parameters, Enzyme’s, Electromagnetic, Immune Cells, Subcellular, Prolong, Carcinogenesis, Angiogenesis, Apoptosis, HIF: Hypoxia Inducing Factor, NLRP: Nucleotide Leucine Rich Protein, ATP: Adenosine Tri Phosphate, TNF ?-: Tumor Necrosis Factor Alpha, AKT: Protein Kinase, mTORC- Mammalian Target of Rapamycin Complex, WNT: Gene Wingless and Protooncogene Integration, MSU: Mono Sodium Urate, PARP: Poly ADP Ribose Polymerase, AIDS: Acquired Immune Deficiency Syndrome, APOBEC: Apolipoprotein B mRNA Editing Enzyme, ROS: Reactive Oxygen Species, PKB: Protein Kinase, NOD: Nucleotide Binding Oligomerization Domain
©2016 Goswami. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.