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Research Article Volume 14 Issue 1
GC-MS analysis, antibacterial, antioxidant and cytotoxic activity of Euphorbia larica Boiss indigenous to Oman
Aya Ali Abdelhamid, Mohammad Sohail Akhtar, Tanveer Alam, Sadri A Said
Received: February 14, 2026 | Published: February 27, 2026
Citation: Abdelhamid AA, Akhtar MS, Alam T, et al. GC-MS analysis, antibacterial, antioxidant and cytotoxic activity of Euphorbia larica Boiss indigenous to Oman. Pharm Pharmacol Int J. 2026;14(1):23-26. DOI: 10.15406/ppij.2026.14.00489
Abstract
Euphorbia is a diverse genus within the Euphorbiaceae family, comprising over 2,000 species and 600 hybrids. Among these, Euphorbia larica—known locally in Arabic as Isbaq—is a vital component of Oman’s indigenous desert vegetation. This study utilized GC-MS analysis to identify the chemical constituents of E. larica leaf oil, revealing 22 distinct compounds. The chemical profile is dominated by monoterpenes (63.6%), followed by sesquiterpenoids (24.16%), triterpenoids (9.2%), and diterpenes (2.8%). Furthermore, the oil underwent biological evaluation using DPPH assays, disc diffusion, and brine shrimp lethality tests, demonstrating significant antioxidant, antibacterial, and cytotoxic activities.
Keywords: Euphorbia larica, GC-MS, antioxidant, antibacterial and cytotoxic
©2026 Abdelhamid, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.