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Conceptual Paper Volume 16 Issue 3
Modulation of the casimir pressure in cerebral microtubules induced by the chanting of the Daimoku (Nam-Myoho-Renge-Kyo): from the single tubulin dimer to the scale of the entire brain
Marco Ruggiero
Received: May 01, 2026 | Published: June 2, 2026
Citation: Ruggiero M. Modulation of the casimir pressure in cerebral microtubules induced by the chanting of the Daimoku (Nam-Myoho-Renge-Kyo): from the single tubulin dimer to the scale of the entire brain. J Neurol Stroke. 2026;16(3):115-118. DOI: 10.15406/jnsk.2026.16.00661
Abstract
The Orchestrated Objective Reduction (Orch OR) theory proposes that consciousness arises from quantum computations within neuronal microtubules. It has previously been suggested that Casimir-Lifshitz forces generated by vacuum fluctuations inside microtubule lumens may influence their conformational dynamics and, consequently, conscious processes. The present study theoretically investigates how the acoustic vibrations produced during the solemn recitation of the Daimoku (Nam-Myoho-Renge-Kyo) in Nichiren Shoshu Buddhist liturgy can modulate Casimir-Lifshitz pressures in cerebral microtubules, extending from the single tubulin dimer to the scale of the entire brain. Spectral analysis of the chanting reveals prominent frequency components, including peaks around 8 Hz, 116 Hz and Solfeggio frequencies. When combined with respiratory oscillations associated with chanting practice, these acoustic and mechanical inputs are predicted to induce nanometric displacements in microtubule structures. Calculations indicate relative changes in Casimir pressure on the order of 15–23% at the single-dimer level, with potential amplification across large-scale synchronized networks in the brain.This interdisciplinary model bridges sacred sound, quantum physics, and neuroscience, offering a novel framework for understanding how contemplative practices may influence brain activity and consciousness. While the theoretical predictions are intriguing, they remain hypotheses requiring experimental validation
Keywords: casimir pressure, Orch OR theory, microtubules, tubulin, Nam-MyohoRenge-Kyo, Daimoku, Solfeggio frequencies, quantum vacuum fluctuations, phononic pumping
©2026 Ruggiero. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.