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Research Article Volume 6 Issue 4
Metallic Nanoparticles as Alternative Antimicrobials
Hiral Soni, Nirmal Kumar JI, Khushal Patel, Rita N Kumar
Received: January 01, 1971 | Published: December 21, 2017
Citation: Soni H, Kumar NJI, Patel K, Kumar RN (2017) Metallic Nanoparticles as Alternative Antimicrobials. J Nanomed Res 6(4): 00165. DOI: 10.15406/jnmr.2017.06.00165
Abstract
Nanoparticles (NPs) of ZnO TiO2 & ZVI were synthesized by sol-gel method and precipitation route. XRD analysis showed that all synthesized nanoparticles were 25-55 nms in size. TEM analysis provided shape of synthesized nano ZnO, TiO2, and ZVI. They were evaluated for their ability to minimize or deteriorate microbial load. For assessment of antimicrobial effect of synthesized nanoparticles, agar well diffusion method was used. Inhibition zone was measured and further minimum inhibitory concentration (MIC) of nanoparticle was evaluated. The obtained results showed that all of the three synthesized nanoparticles possess antimicrobial activity. The experimental results also provided information about changes of microbe growth curve upon the treatment with nanodose.
Keywords: Antimicrobial, Nanodose, Inhibitory, Nanoparticles, Microbial infections, Biofilm, Fabrication, Inorganic, Biodegradable, Polymeric, Agar, Diffractograms, Magnetic, Optical Density, Multidrug
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