Journal of
eISSN: 2574-9943
Submit manuscript...
Clinical Images Volume 3 Issue 5
Abrikossoff’s tumor: Clinical and dermoscopic features
Aicha Elharrouni Alaoui,
Verify Captcha
Regret for the inconvenience: we are taking measures to prevent fraudulent form submissions by extractors and page crawlers. Please type the correct Captcha word to see email ID.
Zakia Douhi, Sara Elloudi, Hanane Baybay, Fz Mernissi
Verify Captcha
Regret for the inconvenience: we are taking measures to prevent fraudulent form submissions by extractors and page crawlers. Please type the correct Captcha word to see email ID.
Department of dermatology, CHU Hassan II, Morocco
Correspondence: Aicha Elharrouni Alaoui, Department of dermatology, CHU Hassan II, FES, Morocco
Received: September 18, 2019 | Published: September 30, 2019
Citation: Alaoui AE, Douhi Z, Elloudi S, et al. Abrikossoff’s tumor: Clinical and dermoscopic features. J Dermat Cosmetol. 2019;3(5):130 DOI: 10.15406/jdc.2019.03.00129
Keywords
Abrikossoff tumor, dermoscopy, granular cell tumor
Clinical Image
A 46-year-old woman, presenting a subcutaneous tumor gradually increasing in size on the right thigh, painless, non-pruriginous evolving for over 7 months. Clinical examination revealed a firm pigmented tumor measuring 3cm and not freely movable; the overlying surface was smooth and free of ulceration. The dermoscopy showed yellowish center with lighter, hypopigmented lines, surrounded by light-brown pigmented network.
A wide excisional biopsy was performed. The histopathological examination showed a proliferation of monotonous cells, large, round or polygonal, with pink and granular cytoplasm. These granules are eosinophilic balls of variable size. Immuno histochemistry confirmed the diagnosis of granular cell tumor, staining positivity for protein S-100.
Granular cell tumors (GCTs) are tumors with a benign proliferation made of large eosinophilic cells with granular cytoplasm. They are rare neoplasms of soft tissue with ubiquitous locations, and are usually benign but on occasion multifocal or malignant. Recently dermoscopy has become an indispensable tool in contemporary dermatological practice. The dermoscopic criteria of GCTs have recently been updated. However the presence of a nodular lesion in combination with yellowish center associated to peripheral network, and pale circles, should lead us to think about GCTs and perform a biopsy for confirmation. The treatment of choice in all the cases is wide excision of the lesion with histologically clear margins. The risk of recurrence requires long-term surveillance. (Figure1-2)
Figure 1 Clinical image: An oval, brown tumor, measuring 3cm.
Figure 2 (a) Dermoscopic image tumor showed yellowish center. (b) With lighter, hypopigmented lines, surrounded by light-brown subtile pigmented network.
Acknowledgments
None.
Conflicts of interest
The authors report no conflicts of interest.
Funding
None.
References
- Ghosh SK. A solitary verrucous nodule on the arm. Granular cell tumor (GCT). Int J Dermatol. 2013;52(6):651–653.
- Scope A, Benvenuto–Andrade C, Agero AL, et al. Nonmelanocytic lesions defying the two–step dermoscopy algorithm. Dermatol Surg. 2006;32(11):1398–1406.
- Popadic M. Dermoscopy of cutaneous Abrikossoff tumor (granular cell tumor) in a pediatric patient. J Am Acad Dermatol. 2015;73(4):e137–e138
- Kanitakis J, Mauduit G, Viac J, Thivolet J. Granular–cell tumor (Abrikosov). Immunohistological study of 4 cases with review of the literature. Ann Dermatol Venereol. 1985;112(11):871–876.
- Kourda M, Marsit N, Elloumi L, et al. A case for diagnosis. Abrikossoff tumor. Ann Dermatol Venereol. 1999;126(5):441–442.
©2019 Alaoui, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.