Inhibin alpha as a tumor marker for early detection of uterine tumors similar to ovarian sex cord tumors
Farkhondeh Pouresmaeili, Shima Mohammadian, Soheila Sarmadi, Aida Mohammadian
Received: March 11, 2024 | Published: January 28, 2025
Citation: Pouresmaeili F, Mohammadian S, Sarmadi S, et al. Inhibin alpha as a tumor marker for early detection of uterine tumors similar to ovarian sex cord tumors. Urol Nephrol Open Access J. 2025;13(1):4-6. DOI: 10.15406/unoaj.2025.13.00361
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Background: Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are a rare type of endometrial sarcoma characterized by uterine stroma. These tumors mimic reproductive cord structures and typically exhibit benign behavior. A thorough evaluation of histological and immunohistochemical features is crucial for accurate diagnosis and effective management of these cases.
Case presentation: This report discusses a 45-year-old Iranian woman who presented with a large uterine mass and subsequently underwent a total hysterectomy and bilateral oophorectomy. Pathological analysis identified the lesion as a uterine sac. Notably, there was a significant difference in Inhibin A levels before and after surgery, suggesting that the tumor was responsible for the secretion of this factor.
Conclusion: We recommend that during the initial assessment of similar patients, the levels of this factor should be included in routine blood tests.
Keywords: Uterine tumors, malignancy, salpingo oophorectomy, case report
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