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Research Article Volume 5 Issue 3
Antiretroviral effectiveness with Cuban generics in patients with HIV/AIDS in the province of Santiago de Cuba
Reinier Besse Díaz
University Clinical and Surgical Hospital Dr. "Ambrosio Grillo Portuondo, Cuba
Received: May 19, 2019 | Published: June 12, 2019
Citation: Díaz DRB, Artiles RAC, Sani VP, et al. Antiretroviral effectiveness with Cuban generics in patients with HIV/AIDS in the province of Santiago de Cuba. MOJ Toxicol. 2019;5(3):106?110. DOI: 10.15406/mojt.2019.05.00163
Abstract
The HIV/AIDS epidemic continues to be a real health problem; one of the most significant progresses in the fight against the epidemic is the highly effective antiretroviral treatment. A descriptive and transversal study was carried out, with retrospective collection of the sample. We used a study universe consisting of all patients with AIDS of the mentioned province, selecting a simple random probabilistic sample of 60 patients with HIV/AIDS, belonging to the province of Santiago de Cuba who graduated from the Internal Medicine service of the General Teaching Hospital Dr. "Juan Bruno Zayas Alfonso" (clinical immunology). Clinical and therapeutic variables were used according to the national program and expert criteria, arriving at precise estimations in the variations of the effectiveness of the therapeutic used of this medication through selected clinical and hematological parameters. The female sex predominated in the conglomerate of patients and there was a greater percentage of recoverability of the evolutionary parameters studied for the male sex. Scheme I showed to be the most used with figures of 41.7%, modifying the parameters of studies such as CD4 and viral load in a beneficial and staggered manner according to the quarters analyzed. The effectiveness of the therapeutic scheme used became evident, based on a marked increase in the values ??of CD4 lymphocytes, and the relevant decrease in viral replication, which translates into a significant decrease in opportunistic diseases.
Keywords: AIDS, antiretroviral effectiveness, viral load, quarters,burden, circulating, viral, analyzed, evolutionary, parameters, therapeutic, scheme, CD4 lymphocytes, opportunistic, diseases
©2019 Díaz. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.