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Case Report Special Issue Lymphology & Phlebology
Classical hodgkin’s lymphoma presenting with hemophagocytosis
Manish J Dave MD, Rabea Khedimi MD, Yelena Averbukh MD
Received: January 01, 1971 | Published: November 26, 2018
Citation: Dave MDMJ, Khedimi MDR, Averbukh MDY. Classical hodgkin’s lymphoma presenting with hemophagocytosis. MOJ Immunol. 2018;6(6):217-219. DOI: 10.15406/moji.2018.06.00230
Abstract
Hemophagocyticlymphohistiocytosis (HLH) is a rare, hyper inflammatory disorder which may be associated with hematologic malignancy. This is a case of fulminant HLH associated with classical Hodgkin's lymphoma. A 42-year-old Malian woman presented with constitutional symptoms and was eventually diagnosed with lymphoma and HLH. Her initial work-up was unrevealing for malignancy and infectious etiology. Hematologic malignancy may be complicated by severe forms of HLH. To ensure better clinical outcomes, physicians should consider initiation of treatment for HLH prior to treatment of lymphoma. This case demonstrates the importance of considering rare conditions in a critically ill, febrile patient while also evaluating for other more common etiologies.
Keywords: HLH, Hemophagocyticlymphohistiocytosis, CD4, HLH, Immune deficiencies, hemophagocytosis, Immunohistochemistry, Infection, Immune deficiencies, Hematologic malignancy, histoplasmosis, Lymphoproliferative malignancy, Immunohistochemistry, Hodgkin’s lymphoma, Cyclophosphamide, Prednisone, Etoposide, Bleomycin
©2018 Dave, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.
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