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Proceeding Proceedings Proceedings 2016

Anaphylactic Shock after Intravenous Injection of Cow's Milk

Öner Özdemir, Elmas Bahri

Department of Pediatrics, Research and Training Hospital of Sakarya University, Turkey

Correspondence: Öner Özdemir, Division of Allergy and Immunology, Department of Pediatrics, Research and Training Hospital of Sakarya University, Faculty of Medicine, Sakarya University, Adnan Menderes Cad, Sağlık Sok No: 195, Adapazari, Sakarya, Turkey, Tel 90-264-444-54-00, Fax 90-264-275-91-92

Received: February 03, 2016 | Published: February 18, 2016

Citation: Elmas B, Özdemir Ö (2016) Anaphylactic Shock after Intravenous Injection of Cow's Milk. MOJ Immunol 3(2): 00079. DOI: 10.15406/moji.2016.03.00079

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Background: Although it is rare in childhood, intravenous injection of foreign substances can cause fatal complications. Most of the cases reported in the literature are accidental intravenous administrations of enteral feeding formulas. To the best of our knowledge, this is the first case of intravenous injection of cow’s milk. In this report, we discuss clinical presentation and treatment of 17-year-old girl nursing student who injected pasteurized homogenized cow’s milk to herself due to curiosity.

Case Report: 17-year-old girl presented to our emergency department after intravenous injection of cow’s milk. During admission, she presented with angioedema, gastrointestinal symptoms, dyspnea, tachycardia associated with resistant hypotension. She then developed leukocytosis and elevated D-dimer levels in laboratory. The patient was diagnosed as having anaphylactic shock with the clinical presentation and cow’s milk specific IgE positivity from her laboratory findings. The patient was initially begun to treat with intravenous fluid, adrenaline, corticosteroids and antihistamines. Inotropes including catecholamines and wide spectrum antibiotics were added into the therapy for resistant hypotension and sepsis prophylaxis. Low molecular weight heparin treatment was given for elevated D-dimer levels and prevention of embolic events. With these therapeutic interventions, there were no signs of sepsis, thrombosis, embolus and multi-organ failure. The patient was discharged without any neurological complications or sequela on the 6th day of hospital admission.

Conclusion: Although sepsis and septic shock development is normally expected after injection of foreign substances such as in this case, interestingly there was an anaphylactic shock caused by patient’s subclinical cow’s milk allergy.



Conflicts of interest

Authors declare that there is no conflict of interest.

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©2016 Elmas, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.