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Mini Review Volume 2 Issue 1
Lipoprotein nanoparticles in diagnosis and treatment of cancer
Amira R Amin, Hatem K Amin
Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt
Received: February 02, 2018 | Published: February 12, 2018
Citation: Amin AR, Amin HK. Lipoprotein nanoparticles in diagnosis and treatment of cancer. MOJ Drug Des Develop Ther. 2018;2(1):15-18. DOI: 10.15406/mojddt.2018.02.00024
Abstract
Lipoproteins are natural endogenous nanoparticles synthesized by human liver that became an important part of Nano medicine. Due to their high compatibility, safety and stability, many studies have been conducted to investigate utilization of LDL and HDL as Nano vectors. Modified lipoproteins, synthetic recombinant lipoproteins as well as analogous Apo lipoproteins have been formulated for the same purposes. Applications of lipoprotein nanoparticles in targeted delivery of multiple cancer imaging probes and anticancer chemotherapeutic and photodynamic treatments will be briefed.
Keywords: nanoparticles, lipoproteins, LDL, HDL, anticancer, chemotherapy, drug delivery, photodynamic therapy, imaging, lipid nanotechnology
©2018 Amin, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.