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Short Communication Volume 4 Issue 1
Total synthesis of the civet constituent (-)-2-((2R, 6R)-6-methyltetrahydro-2H-pyran-2-yl) acetic acid
Fátima Garrido, Hugo Santalla, Generosa Gómez, Yagamare Fall
Departamento de Química Orgánica, Facultad de Química and Instituto de Investigación Sanitaria Galicia Sur (IISGS), University of Vigo, Campus Lagoas de Marcosende, 36310 Vigo, Spain
CITACA-Cluster de Investigación e Transferencia Agroalimentaria do Campus Agua, Universidad de Vigo, Ourense Spain
Received: January 10, 2020 | Published: January 23, 2020
Citation: Garrido F, Santalla H, Gómez G, et al. Total synthesis of the civet constituent (-)-2-((2R, 6R)-6-methyltetrahydro-2H-pyran-2-yl) acetic acid. MOJ Biorg Org Chem. 2020;4(1):7-9. DOI: 10.15406/mojboc.2020.04.00103
Abstract
We describe the total synthesis of a glandular secretion of the Civet Cat, using tri-O-acetyl-D-glucan, a cheap and commercially available chiral building block.
Keywords: Tetrahydropyran, Civet cat compound, Natural product, Glandular secretion, Chiral reagent, MOM protection, Wolf-Kushner reaction, Alcohol
©2020 Garrido, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.