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Research Article Volume 4 Issue 1
Synthesis and characterization of benzoylatedsulfamoyl carboxylic acids
Melford C Egbujor, Uchechukwu C Okoro, Chikamso M Udeh, Erasmus O Anieze, Ugochukwu B Amadi, Innocencia C Chidebelu, Chioma G kenwa Ani
Department of Industrial Chemistry, Renaissance University, Nigeria
Department of Pure and Industrial Chemistry, University of Nigeria, Nigeria
Chemistry Unit, AkanuIbiam Federal Polytechnic Unwana Ebony State, Nigeria
Received: February 04, 2020 | Published: February 21, 2020
Citation: Egbujor MC, Okoro UC, Udeh CM, et al. Synthesis and characterization of benzoylated sulfamoyl carboxylic acids.MOJ Biorg Org Chem.2020;4(1):22?25. DOI: 10.15406/mojboc.2020.04.00106 DOI: 10.15406/mojboc.2020.04.00106
Abstract
The systematic synthesis of new benzoylated sulfamoyl carboxylic acids derivatives is reported. The process involved the mild reaction of benzyl chloride with sulfamoyl carboxylic acids in the presence of sodium hydroxide via benzoylation reaction mechanism. The characterization of the compounds was done using FTIR,1H-NMR, 13C-NMR and elemental analysis.The synthesized compounds were found to agree perfectly with the spectra data confirming the successful synthesis of benzoylated sulfamoyl carboxylic acids. The yields of the compounds were between 60% and 99% while their melting points were in the range 105oC to 113oC. Compounds 2b (3.04g, 98.7%) and 2g (3.04g, 98.5%) gave the highest yields while compound 1a (1.50g, 62.5%) gave the smallest yield. The reaction methodology was found to be efficient thereby resulting to excellent yields of benzoylated sulfamoyl carboxylic acids.
Keywords: benzoylatiosulphamoyl carboxylic acids, benzyl chloride, synthesis, antimicrobial, tetramethyl silage, FTIR spectra, NMR spectrophotometer
©2020 Egbujor, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.