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Short Communication Volume 3 Issue 1
Some comments on the Cyclodextrin solubilities
Laszlo Jicsinszky
Department of Drug Science and Technology, University of Turin, Italy
Received: February 05, 2019 | Published: February 19, 2019
Citation: Jicsinszky L. Some comments on the Cyclodextrin solubilities. MOJ Biorg Org Chem. 2019;3(1):11-13. DOI: 10.15406/mojboc.2019.03.00091
Abstract
The cyclodextrin (CD) solubilities in various solvent systems are discussed. The erroneous aqueous solubility-temperature equations have been substituted with simpler ones. The new equations calculate the CD solubilities in water more accurately. Re-calculation of the literature data of organic solvent-water mixtures from molar fractions to volume percentage of organic solvents resulted in a more user friendly data.
Keywords: water-organic solvent mixtures, aqueous solubility equation, nonlinear curve fitting, hydroxyl rims, cyclodextrins, crystalline state, complex formation, solvent-water mixtures, aqueous solubility, molecule solubility
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