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Review Article Volume 6 Issue 1
Mesenchymal stem cells as potential regenerative treatment for pre-eclampsia: a review
Sarah Tanner, Vincent Gallicchio
Received: February 19, 2020 | Published: February 27, 2020
Citation: Tanner S, Gallicchio V. Mesenchymal stem cells as potential regenerative treatment for pre-eclampsia: a review. J Stem Cell Res Ther. 2020;6(1):56?62. DOI: 10.15406/jsrt.2020.06.00141
Abstract
Research in regenerative medicine and tissue engineering has continued to show advancement towards being a potential cure for autoimmune disorders. Specifically, mesenchymal stem cells show great potential in tissue regeneration and repair. Preeclampsia is a systematic endothelial dysfunction disorder that leads to hypertension and proteinuria. This occurs when syncytiotrophoblast are under stress and can’t properly remodel the spiral arteries of the placental bed. Mesenchymal stem cells are being used to reverse the damage already done by pre-eclampsia and restore equilibrium. Current research shows promising outcomes when tested on animals. Experiments are being ran to test all aspects of the disorder from regeneration and reconstruction to genetic foundations.
Keywords: pre-eclampsia, Mesenchymal Stem Cells, Hypertension, T-Helper Cell 1/T-helper Cell 2 (Th1/Th2), Cytokines
©2020 Tanner, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.