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Journal of
eISSN: 2475-5540

Stem Cell Research & Therapeutics

Short Communication Volume 11 Issue 1

Alpha fold 3D boltz 2 protenix chai discovery systems: reliable results? When concerning sea star antibody- HRP antigen complex study

Michel Leclerc

Received: May 25, 2026 | Published: June 9, 2026

Citation: Leclerc M. Alpha fold 3D boltz 2 protenix chai discovery systems: reliable results? When concerning sea star antibody- HRP antigen complex study. J Stem Cell Res Ther. 2026;11(1):225-227. DOI: 10.15406/jsrt.2026.11.00220

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Abstract

Recently, we have presented the first 3D images of the sea star Antibody (anti-HRP) - HRP Antigen complex in Alpha Fold 3, with minor details. In the present study, we used 4 systems of 3D representation, which are all issued from Alpha Fold, to illustrate this same complex. It appears clearly that these models, by using the ITPM parameter give contradictory results. Nevertheless, we start from the principle that in Science, we must be transparent. Nevertheless, it’s the first time, we present such models concerning an invertebrate primitive antibody: you understand that comparisons with other antibody 3D models seem difficult to establish, in the present time.

Keywords: sea star antibody, anti-HRP antibody, HRP antigen, alphafold 3, antigen– antibody complex, 3D molecular modeling, invertebrate immunity, protein–protein interactions

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©2026 Leclerc. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.