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Research Article Volume 16 Issue 2
Vaccination coverage and immune response among children and adolescents living with HIV/AIDS in a tertiary hospital in Southern Brazil
Savas Sobral Silveira, Marina Pinheiro da Silva Bolinsenha, Yasmin Oliveira Rossoni, Sinis Sobral Silveira, Giuliana Lugarini, Carolina Chong e Silva, Tony Tannous Tahan, Tatiane Emi Hirose, Betina Mendez Alcântara Gabardo, Cristina de Oliveira Rodrigues, Andrea Maciel de Oliveira Rossoni
Received: May 27, 2026 | Published: June 9, 2026
Citation: Silveira SS, Bolinsenha MPS, Rossoni YO, et al. Vaccination coverage and immune response among children and adolescents living with HIV/AIDS in a tertiary hospital in Southern Brazil . J Pediatr Neonatal Care. 2026;16(2):70-72. DOI: 10.15406/jpnc.2026.16.00622
Abstract
Introduction: Children and adolescents living with HIV/AIDS are more vulnerable to vaccine-preventable diseases due to immunological impairment. Adequate vaccination coverage and immune response are essential to reduce morbidity and improve quality of life in this population. Objective: To describe adherence to the vaccination schedule among children and adolescents living with HIV/AIDS in a tertiary healthcare service in southern Brazil, as well as the immune response to selected vaccines. Methods: This was an observational, cross-sectional study with retrospective data collection, evaluating the vaccination profile of patients followed at a pediatric infectious diseases outpatient clinic in a tertiary care center in Paraná, Brazil, during the year 2022. Results: A total of 49 patients participated in the study. The median age at diagnosis was 4.0 years (0–10), and the current median age was 10.0 years (1–17). Females accounted for 53.1% of the sample, and 67.3% of participants were under the care of parents or extended family members. Vaccination coverage for the routine immunization schedule was 83.7%, whereas coverage for complementary vaccines was 76.2%, ranging from 42.9% to 98.0%. No statistically significant association was observed between complete hepatitis vaccination schedules and the presence of antibodies. Conclusion: Vaccination coverage rates among children and adolescents living with HIV/ AIDS were below desirable levels, and low rates of detectable antibodies against hepatitis A and B were observed.
Keywords: HIV, child, hepatitis B, hepatitis A, vaccination schedule
©2026 Silveira, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.