Journal of eISSN: 2373-4426 JPNC

Pediatrics & Neonatal Care
Case Report
Volume 2 Issue 2 - 2015
Pyloric Duplication: About Two Cases
Y Ben Ahmed*, S Ghorbel, A Charieg, F Nouira, R Khemekhem, S Jlidi and B Chaouchi
Department of Pediatric surgery, Tunis Medical School, Tunisia
Received: October 31, 2014 | Published: April 20, 2015
*Corresponding author: Y Ben Ahmed, Pediatric surgeon, Department of Pediatric surgery, Tunis Medical School, Tunis, Tunisia, Tel: +33624902112; Email: @
Citation: Ahmed YB, Ghorbel S, Charieg A, Nouira F, Khemekhem R, et al. (2015) Pyloric Duplication: About Two Cases. J Pediatr Neonatal Care 2(2): 00065. DOI: 10.15406/jpnc.2015.02.00065


Pyloric duplication cyst is a rare congenital anomaly. Few cases have been described in the literature. We report two cases of 2 and 5 year-old girl. The diagnosis was suspected on ultra sonography and upper gastrointestinal series and confirmed by surgery and histopathologic examination. Resection was total in one case and partial in the other. Pyloroplasty was associated. Post operative was unfaithful.
Keywords: Duplication; Pylorus; Resection; Pyloroplasty


Duplication cysts of the pylorus are the rarest of gastrointestinal duplications. Few cases have been described in the literature [1]. In most cases preoperative diagnosis is not made [2]. To our knowledge, no more than 20 cases of pyloric duplication have been reported in the English literature [1-18], most of them were extra luminal masses. Here in, we describe two cases with pyloric duplication cyst.

Case 1

A five year old girl was hospitalized because she has suffered from abdominal pain and non bilious vomiting for a month. Her physical examination was unremarkable except epigastric tenderness. Biologic exams were normal specifically amylasemia. An upper gastrointestinal barium contrast study revealed in spite of a sus carina reflux, a pyloric and antrum deformation, with an extrinseque compression. Oesogastric fibroscopy showed a deformation of pylorus. During surgery, pyloric cystic duplication of 2 cm*3cm was noticed (Figure 1). By opening the mass, we found 3 cystic formations; the bigger one has a common wall with the posterior face of the pylorus and the antrum with a narrowed communication. The duplication was resected as well as the common wall and a pyloroplasty was performed (Figure 2). There were no postoperative problems and the post operative barium - meal examination was normal.

Figure 1: A pyloric cystic duplication of 2 cm*3cm.

Figure 2: Duplication resection as well as the common wall.

Case 2

A two year old girl was presented in emergency for paroxystic abdominal pain without vomiting or other signs. The physical exam showed an epigastrium mass of 3 cm which is round, tense, smooth and non tender beneath the umbilicus. Biologic exams were normal. Abdominal ultrasound with computer tomography revealed a cystic epigastric mass of 4.3 cm with a wall that took contrast (Figure 3). Around this mass there was an ultrasound aspect of volvulus (Figure 4). A barium-meal examination demonstrated delayed gastric emptying through a narrowed pyloric antrum, which was distorted by a non communicating mass (Figure 5). At laparotomy, a cystic mass measuring approximately 4 × 3 cm was identified anterior and lateral to the pyloric channel, sharing a common wall. The mass compressed the pyloric channel, resulting in partial gastric outlet obstruction. The duplication cyst did not communicate with the pyloric channel. Most of the cyst was excised, and the mucosa of the remnant cyst wall was cauterized. Histologic examination revealed gastric mucosa with a smooth muscle coat, which was consistent with a pyloric duplication cyst. No aberrant tissue was seen. The postoperative course was uneventful. The patient was asymptomatic 4 years later.

Figure 3: Computer tomography: Cystic epigastric mass with a fine wall ( ☆ ) that took contrast.

Figure 4: Ultrasound aspect of volvulus around the mass.

Figure 5: A barium-meal examination: Narrowed pyloric antrum distorted from below by a non communicating mass.


  1. Congenital duplications are uncommon congenital lesions. They may arise anywhere in the gastrointestinal tract from the mouth to the anus with an incidence of 1 in 4500 births [9,13]. This spherical or tubular cystic structure is lined with alimentary tract epithelium and has smooth muscle in its wall. Less than 4% of all gastrointestinal duplications (GID) involve the stomach [3,19]. Pyloric duplication cysts are uncommon lesions; most of them are extraluminal masses. The female-to-male ratio is 2:1. The vast majority is discovered in the 1st year of life. Only one third of the duplications is present in the neonatal period [19,20]. In literature, ages vary between 1 day and 2 years old [15,21]. Our patients are the oldest reported in case of pyloric duplication.
  2. Gastrointestinal duplication (GID) has an embryonic origin, it probably develops in the sixth week of embryonic life but the etiology has not been elucidated. Several theories have been proposed to explain their development. These include the persistence of embryonic diverticulae during alimentary development, abortive attempts at twinning, intrauterine vascular accidents, and recanalization with fusion of embryological longitudinal folds [2,3,11,20,22]. However, none of these theories alone is able to explain the full diversity of these lesions. The most attractive theory is the split notochord syndrome (adhesions of entoderm to neuroectoderm).
  3. The presentation of gastrointestinal duplication can vary according to the age and the localization. Some GID may be totally asymptomatic, identified on routine physical examination or during investigations for other problems. Common clinical manifestations of pyloric duplications include a palpable abdominal mass and non bilious vomiting which is almost present in all the cases of literature [1-18]. Bleeding, intussusception can be an occasion for discovering such unusual anomalies [3,20]. Most pyloric duplication cysts have no communication with the adjacent bowel tract and have no complications [8]. In the first case pyloric duplication have communication with digestive tract.
  4. With the increasing use of prenatal ultrasound scan, some are now being identified In utero [23]. Five cases were reported in prenatally diagnosis [19]. The accurate preoperative diagnosis of GID, especially pyloric duplication, is challenging. Conventional plain radiographic studies are nonspecific. Upper gastrointestinal tract contrast studies may show an extrinsic filling defect. Ultrasound is the most common modality. It may reveal the inner hyperechoic and outer hypoechoic layers (double-wall sign) that are typical of duplication cysts considered by Deftereos as a confirmation of the diagnosis [4,24]. However, in the case we described, ultrasound showed, only, an anechoic cystic mass with a single hyperechoic wall, and the typical double-wall sign was not reached. Computer tomography CT is not only useful for making a correct diagnosis of the cysts duplications but also provides better information than US regarding the exact extension and limits of cystic masses [8]. Nuclear scans using radioisotopes may show tracer uptake by ectopic gastric mucosa. Magnetic resonance imaging studies are useful in demonstrating the relationship with other structures [4,15]. If, after appropriate investigations, the diagnosis remains unclear, we suggest that laparoscopy should be used to confirm the diagnosis [22]. Hypertrophic pyloric stenosis, pyloric atresia and congenital antral webs should be included in the differential diagnosis in case of newborn. We can also include mesenteric cysts, retroperitoneal cysts, lymphangioma, and in female patients, ovarian cysts [10].
  5. Definitive treatment of GID involves ideally total excision, which often requires resection of the adjacent bowel as duplication cysts usually share a common wall with the bowel and so a restoration of continuity of the lumen [25]. However, in some cases, because of extensive size or location, alternate procedures such as subtotal excision with removal of mucosa or its cauterization without resection of the contiguous pylorus can be made. In our second case, considering important adhesions, we did subtotal excision. This approach allows rapid postoperative recovery, but any procedure should ideally ensure removal of mucosa to prevent subsequent malignant transformation into carcinoma in later adulthood [1,2]. Laparoscopy should be utilized liberally in patients with atypical presentation of inflammatory bowel disease or when the diagnosis of abdominal cystic masses in neonates or infants is unclear [18,25].


Duplications involving the pylorus are particularly rare. Diagnostic studies, including ultrasonography, an upper gastrointestinal barium study, and regarding the case endoscopy, and CT, are useful in establishing the preoperative diagnosis. Surgery is the undisputed mainstay of management. It ranges from simple excision to pyloroantrectomy. In all surgical procedures, it is essential to remove the entire lining of the duplication cyst.


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