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Research Article Volume 13 Issue 2
In Vitro antibacterial activity of moringa leaves (Moringa oleifera) and aloe vera (Aloe barbadensis Miller) against escherichia coli and klebsiella pneumoniae
Oluwasegun Olatunji
Received: July 01, 2025 | Published: July 24, 2025
Citation: Olatunji O. In Vitro antibacterial activity of moringa leaves (Moringa oleifera) and aloe vera (Aloe barbadensis Miller) against escherichia coli and klebsiella pneumoniae. J Microbiol Exp. 2025;13(2):54-61. DOI: 10.15406/jmen.2025.13.00433
Abstract
The medicinal properties shown by different medicinal plants are as a result of the present phytochemicals in the plants. These phytochemicals are important sources for the treatment of diseases. Different phytochemicals have an extensive range of activities, which helps to boost the immune system and give resistance against disease to protect the body from harmful pathogens. The study was aimed to determine the phytochemicals constituents and antibacterial activity of Moringa oleifera leaf and Aloe vera extracts against Two (2) bacteria associated with gastroenteritis namely; Escherichia coli and Klebsiella pneumoniae. The bacterial isolate was obtained from Microbiology Laboratory of Gombe State University, Gombe. Phytochemical screening of the leaf extract was conducted in the Plant Science Laboratory to ascertain the presence and number of bioactive components present in the both plant extract using Two (2) solvent (Ethanol and Distilled Water). The antimicrobial assay of the leaves extracts was performed using the disc diffusion method. The qualitative phytochemicals screening of the extract indicated the presence of Alkaloid, flavonoids, phenol, glycosides, saponin and tannin while steroid is found absent in both plant samples. The result shows that the extracts were active against the microorganisms. The Ethanol extract showed highest activity against the bacterial isolates than aqueous extracts. It is concluded that ethanol extract has higher effect and possesses more antibacterial activities compared to the aqueous extracts, which is attributable to the fact that ethanol extracted more of the bioactive components of the plant compared to the aqueous.
Keywords: Antibacterial-activity, Gastroenteritis, Phytochemical, Screening, Escherichia coli, Klebsiella pneumoniae
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