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Case Report Volume 6 Issue 1
Dengue Meningoenchephalitis: A Rare Complication in a Dengue Patient with Non Haemorrhagic Manifestations- Case report
Senanayake S, Chinthaka SWGJW, Weerarathna WAPSR, Dematapitiya BRCM, Anfas AAM, Satharasinghe RL, Gunasekara H
Department of Pharmacology, University of Sri Jayawardenepura, Sri Lanka
Received: September 24, 2017 | Published: January 9, 2018
Citation: Senanayake S, Chinthaka SWGJW, Weerarathna WAPSR, Dematapitiya BRCM, Anfas AAM et al. (2018) Dengue Meningoenchephalitis: A Rare Complication in a Dengue Patient with Non Haemorrhagic Manifestations-Case report. J Microbiol Exp 6(1): 00178. DOI: 10.15406/jmen.2018.06.00178
Abstract
Dengue fever is one of the most common mosquito-borne infectious diseases prevalent in South Asia with recent epidemic outbreaks creating a massive health burden on socio-economic status on Sri Lankans. Dengue is a self-limiting febrile viral illness with fewer predilections to the central nervous system (CNS). We report a case of a 19 year-old boy treated for simple dengue fever without hemorrhagic manifestations, who develop features of meningism on day 7 of illness. Non-contrast computerized tomography (CT) and magnetic resonance imaging (MRI) of the brain was normal. An electroencephalogram (EEG) showed generalized slowing with evidence of encephalopathy and CSF showed a lymphocytic pleocytosis with positive dengue IgM antibody. The patient developed signs of recovery on day 12 of illness, and he was followed up in the clinic, with no residual neurological sequel observed at 3 months. This depicts direct viral extension of dengue virus to the central nervous system, which is rarely documented in uncomplicated dengue fever.
Keywords: Dengue, Dengue meningoencephalitis, Non-haemorrhagic manifestations, Infections, Tropics, Serotypes, Hemorrhagic, Hepatosplenomegaly, Aminotransferase, Prothrombin, Fluid, Platelet, Abnormalities, Brain, Meningism
©2018 Senanayake, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.