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Review Article Volume 12 Issue 5
Insights and treatment strategies for coronary artery disease
Shi Claire, Tawil Bill
Received: August 25, 2025 | Published: September 15, 2025
Citation: Claire S, Bill T. Insights and treatment strategies for coronary artery disease. J Appl Biotechnol Bioeng. 2025;12(4):188-196. DOI: 10.15406/jabb.2025.12.00402
Abstract
Coronary artery disease (CAD), which is also referred to as coronary heart disease (CHD) is a condition in which coronary arteries are unable to supply oxygen-rich blood to the heart muscle. There is no cure for CAD, but it can be managed through revascularization strategies that will be discussed in this review, such as the less invasive strategy of percutaneous coronary intervention (PCI) and the more invasive surgical option, coronary artery bypass grafting (CABG). In this review, we will cover the physiology of normal coronary circulation and the pathophysiology of atherosclerotic plaque formation. This review will also include an analysis of the coronary artery disease market, specifically the PCI market and the CABG market. Finally, this review will discuss emerging tissue engineering approaches to CAD treatment that incorporate more biologically integrated or regenerative strategies.
Keywords: coronary artery disease, percutaneous coronary intervention, coronary artery bypass grafting, revascularization, tissue engineering, regenerative medicine
©2025 Claire, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.