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Gastroenterology & Hepatology: Open Access

Editorial Volume 4 Issue 3

Epidemiology of HCC in Egypt

Mohamed Shaker

Department of Tropical medicine, Ain Shams University, Egypt

Correspondence: Mohamed Shaker, Department of Tropical medicine, Ain Shams University, 15 Road 254 Degla Maadi, Cairo, Egypt, Tel 202-29810740; 201001888364

Received: January 12, 2016 | Published: February 19, 2016

Citation: Shaker M (2016) Epidemiology of HCC in Egypt. Gastroenterol Hepatol Open Access 4(3): 00097. DOI: 10.15406/ghoa.2016.04.00097

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Editorial

Hepatocellular carcinoma is a global problem and its epidemiological data varies from place to place. In Egypt HCC is one of the health problems facing the health authorities. Egypt is the sixth largest country in the middle east and arab world, it is the Third largest country in Africa, it is the fifteenth most populous nation in the world about 90 million inhabitants. According to a study published by El-Zayadi et al.,1 they reported almost 2 folds increase in HCC among chronic liver disease patients over a decade. In the hepatoma group Ain Shams University which is the first multidisciplinary team dealing with HCC in Egypt starting since March 2002 the following graph (Figure 1)

Figure 1 Annual number of HCC cases per year.

The major risk factor for HCC is HCV infection 93% of our patients showed HCV Ab. HCV burden in Egypt.

HCV prevalence in 15-59 years old, DHS Egypt, 2008 (n=11,126) . Overall HCV Ab prevalence: 14.7% (95% CI =13.9% -15.5%). Overall HCV viremia: 9.94% (95% CI=9.40% -10.5%) Estimated 6 million HCV chronic infections in Egypt. Looking in our data of 2783 patients we found that the peak age group for HCC was from 50-70 years with a mean age of 58.7 years. Our male to female ratio 6:1. The published data of the national cancer institute showed variable data according to the different governorates, so in Aswan overall the ASIR was 13.1/100000 in Minya it was 25.8/10000 while in Demietta it was 61.5/100000 (Figure 2).2

Figure 2 Epidemiology of Hepatocellular Carcinoma in Egypt.

Figure 3 BCLC HCC Staging at time of Diagnosis.

Biopsy

AFP > 200

Imaging

Imaging & AFP

2%

1%

59%

38%

Table 1 Criteria of diagnosis in 2783 Egyptian HCC patients
91% of our patients were diagnosed by the means of triphasic spiral CT.

Acknowledgments

None.

Conflicts of interest

Author declare that there is no conflict of interest.

Funding

None.

References

  1. el-Zayadi AR, Badran HM, Barakat EM, et al. Hepatocellular carcinoma in Egypt: a single center study over a decade. World J Gastroenterol. 2005;11(33):5193–5198.
  2. http://www.cancerregistry.gov.eg
Creative Commons Attribution License

©2016 Shaker. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.

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