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Review Article Volume 10 Issue 1
Review: Cartilage tissue engineering treatments for chondral defects and osteoarthritis
Gully Dominic, Tawil Bill
Received: June 28, 2024 | Published: July 12, 2024
Citation: Dominic G, Bill T. Review: Cartilage tissue engineering treatments for chondral defects and osteoarthritis. Adv Tissue Eng Regen Med. 2024;10(1):31-37. DOI: 10.15406/atroa.2024.10.00152
Abstract
Osteoarthritis (OA) is one of the most common musculoskeletal disorders, affecting 32.5 million individuals within the United States and more than 590 million globally. Various treatment options exist for cartilage defects and osteoarthritis, including palliative care, surgical intervention, and autologous or allogeneic chondrocyte transplantation, but they contain various limitations that limit their application. Cartilage tissue engineering holds promise as a viable solution for cartilage regeneration. This paper will discuss the anatomy and physiology behind articular cartilage, analyze the pathogenesis of osteoarthritis, explore relevant market information for the cartilage treatments, review existing treatment techniques and products on market, review recent trends in clinical trials, and introduce a potential novel cartilage tissue engineering product.
Keywords: cartilage, tissue engineering, scaffolds, osteoarthritis, chondral defects
©2024 Dominic, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.