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Research Article Volume 5 Issue 2
Computer assisted stereotactic transplantation of human neural stem cells in Parkinson’s disease
Taihua Wang, Yanzhong Xue, Xiuxiu Li, Shouliang Pang, Yuguo Wang, Jinguo Yao, Jianfeng Zhou, Peilai Hao
Department of Neurology, Interventional Hospital of Shandong Red Cross Society, China
Received: September 03, 2018 | Published: April 3, 2019
Citation: Wang T, Xue Y, Li X, et al. Computer assisted stereotactic transplantation of human neural stem cells in Parkinson’s disease. Adv Tissue Eng Regen Med Open Access. 2019;5(2):57-59. DOI: 10.15406/atroa.2019.05.00100
Abstract
Objective: To explore the efficacy and safety of computer assisted stereotactic transplantation of human neural stem cells on Parkinson’s disease (PD).
Method: With the guidance of CT and MRI image mergence, we transplanted 4×107 neural stem cells into the putamen and lateral ventricle of seventeen PD cases by stereotactic surgery. The transplantation site was located in the contralateral side of the symptoms and signs.
Result: After three months follow-up, the effective rate of cell transplantation was 82.4% in the contralateral site and 64.7% in the ipsilateral site. Only a minority of cases had mild dizziness and hemiparesis, but the duration was short.
Conclusion: The therapy, computer assisted stereotactic transplantation of human neural stem cells in the treatment of PD, is safe and efficient.
Keywords: human neural stem cells, stereotaxic technique, cells transplantation, image mergence, Pakinson’s disease
©2019 Wang, et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and build upon your work non-commercially.