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Mini Review Volume 5 Issue 1
Assessment of drinking water quality at the cellular level
Maya Vergolyas
International academy of ecology and medicine, Kiev, Ukraine
Received: December 17, 2018 | Published: March 29, 2019
Citation: Vergolyas M. Assessment of drinking water quality at the cellular level. Adv Tissue Eng Regen Med Open Access. 2019;5(1):53-55. DOI: 10.15406/atroa.2019.05.00099
Abstract
To assess the quality of drinking water, blood cells of test-organisms and human peripheral blood lymphocyte cultures were examined. The prospects of using hematological parameters of test organisms and humans in biotesting are shown. The method consists in determining the action of toxicants on specially selected organisms under standard conditions with the registration of changes at behavioural, physiological, cellular and sub cellular levels. As an optimal set for determining some structural and functional changes in the cell genome due to toxic effects, a micronucleus test and a quantitative indicator of blood lymphocytes were proposed as a biomarker. Particular attention is paid to assessing the risk to human health of those factors and substances whose genotoxicity and cytotoxicity are detected using blood cell biomarkers.
Keywords: genotoxicity, blood cells, micronucleus test, drinking water, cytotoxicity
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